翻訳と辞書 Words near each other ・ Mhasin Fadlalla ・ Mhasla ・ Mhasoba ・ Mhasurne ・ Mhaswad ・ Mhaswad Dam ・ Mhaydseh ・ MHC ・ MHC class I ・ MHC class I polypeptide-related sequence A ・ MHC class I polypeptide-related sequence B ・ MHC class II ・ MHC Dmitrov ・ MHC Krylya Sovetov ・ MHC Martin ・ MHC multimer ・ MHC restriction ・ MHD ・ MHDYS ・ MHealth ・ Mhee Noi ・ Mheer ・ MHEG-5 ・ Mheibes ・ Mhelliah ・ Mher Avanesyan ・ MHF (disambiguation) ・ MHG ・ MHH ・ MHH Franssen Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク MHC multimer ： ウィキペディア英語版 MHC multimer MHC multimers are oligomeric forms of MHC molecules, designed to identify and isolate T-cells with high affinity to specific antigens amid a large group of unrelated T-cells. Multimers generally range in size from dimers to octamers; however, some companies (such as Immudex) use even higher quantities of MHC per multimer. Multimers may be used to display class 1 MHC, class 2 MHC, or nonclassical molecules (e.g. CD1d) from species such as monkeys, mice, and humans. == Background == Since T-Cell Receptors have a low affinity for their MHC counterparts, it was historically problematic to label T cells effectively using single MHC-T-cell interactions.〔Nepom, Gerald T. "MHC Multimers: Expanding the Clinical Toolkit," ''Clinical Immunology'', Vol 6 (2003), pp. 1-4.,Antigen. 106 (2003), pp. 1-4.〕 However, in 1996 it was proposed by John Altman to use a complex of multiple MHC molecules to form a more stable bond between corresponding T-cells.〔Bakker, Arnold; Schumacher, Tom. "MHC Multimer Technology: Current Status and Future Prospects," ''Current Opinion in Immunology'', Vol. 17, No. 4 (August 2005), pp. 428-433.〕 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「MHC multimer」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.